Algorithms in Bioinformatics: 15th International Workshop, by Mihai Pop, Hélène Touzet

By Mihai Pop, Hélène Touzet

This e-book constitutes the refereed court cases of the fifteenth overseas Workshop on Algorithms in Bioinformatics, WABI 2015, held in Atlanta, GA, united states, in September 2015. The 23 complete papers provided have been rigorously reviewed and chosen from fifty six submissions. the chosen papers disguise a variety of themes from networks to phylogenetic reports, series and genome research, comparative genomics, and RNA constitution.

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Extra info for Algorithms in Bioinformatics: 15th International Workshop, WABI 2015, Atlanta, GA, USA, September 10-12, 2015, Proceedings (Lecture Notes in Computer Science)

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Biclustering with flexible plaid models to unravel interactions between biological processes. IEEE/ACM TCBB (2015). 2388206 14. : A structured view on pattern miningbased biclustering. Pattern Recognition (2015). com/ science/article/pii/S003132031500240X 15. : Bicpam: pattern-based biclustering for biomedical data analysis. Algorithms Mol. Biol. 9(1), 27 (2014) BicNET: Efficient Biclustering of Biological Networks 15 16. : Pattern-based biclustering with constraints for gene expression data analysis.

Networks with Unknown Node Mapping Topological Alignments. Here, the edge-weighted version of WAVE is comparable or superior to the edge-unweighted version under MI-GRAAL’s NCF for two out of three alignment quality measures (Fig. 1 in the Appendix). Under GHOST’s NCF, the edge-weighted version of WAVE is rarely favored in this Simultaneous Optimization of both Node and Edge Conservation 27 Table 1. Improvements of an edge-weighted version of WAVE over its edge-unweighted counterpart, over all evaluation tests in which the edge-weighted version is the superior one.

Hence, the following measure, S3 , was introduced recently to penalize for misaligning edges in both the smaller and the larger network [6]. |E ∩E | H Symmetric Substructure Score (S 3 ). S3 is defined as S 3 = |EG |+|E G |−|E × H G ∩EH | 3 100 % [6]. Thus, S keeps advantages of both EC and ICS while addressing their drawbacks. S3 was already shown to be the superior of the three measures [6]. Thus, we discard EC and ICS measures from further consideration, and instead, we report results for S3 .

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